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Genetic distribution of Streptococcus pyogenes isolated through a surveillance system to assess respiratory infection pathogens in Korea, 2007-2018
- Date2019-05-02 20:14
- Update2019-11-19 19:17
- DivisionDivision of Strategic Planning for Emerging Infectious Diseases
- Tel043-719-7271
Genetic distribution of Streptococcus pyogenes isolated through a surveillance system to assess respiratory infection pathogens in Korea, 2007-2018
Kim Hwanhee, Jung Sang Oun, Yoo Jaeil, Hwang Kyu Jam
Division of Bacterial Diseases, Center for Laboratory Control of Infectious Disease, KCDC
Acute pharyngitis is a common respiratory disease caused by bacterial and viral infections. Streptococcus pyogenes (group A streptococci; GAS) is one of the prevalent pathogens that cause bacterial pharyngitis. M protein is the major virulence factor used for the classification of GAS into various emm types. emm type can be the marker of molecular epidemiological investigation of GAS diseases. In this study, S. pyogenes isolates were collected through a surveillance system and tested to determine the prevalence of pharyngitis GAS emm types in Korea. The common emm types in all isolates were emm 12.0, emm 89.0, emm 4.0, emm 1.0, and emm 12.0. However, the most prevalent GAS emm type varies in isolates collected in different years: in 2007-2009, emm 1.0; in 2009-2011, emm 12.0; and in 2015-2018, emm 28.0. In addition, emm genotypes of GAS may vary every year or with time. Hence, continuous studies are necessary to monitor the epidemiological changes of GAS in Korea.
Keywords: Streptococcus pyogenes, Group A streptococcus, Pharyngitis, Respiratory infection, emm type
Kim Hwanhee, Jung Sang Oun, Yoo Jaeil, Hwang Kyu Jam
Division of Bacterial Diseases, Center for Laboratory Control of Infectious Disease, KCDC
Acute pharyngitis is a common respiratory disease caused by bacterial and viral infections. Streptococcus pyogenes (group A streptococci; GAS) is one of the prevalent pathogens that cause bacterial pharyngitis. M protein is the major virulence factor used for the classification of GAS into various emm types. emm type can be the marker of molecular epidemiological investigation of GAS diseases. In this study, S. pyogenes isolates were collected through a surveillance system and tested to determine the prevalence of pharyngitis GAS emm types in Korea. The common emm types in all isolates were emm 12.0, emm 89.0, emm 4.0, emm 1.0, and emm 12.0. However, the most prevalent GAS emm type varies in isolates collected in different years: in 2007-2009, emm 1.0; in 2009-2011, emm 12.0; and in 2015-2018, emm 28.0. In addition, emm genotypes of GAS may vary every year or with time. Hence, continuous studies are necessary to monitor the epidemiological changes of GAS in Korea.
Keywords: Streptococcus pyogenes, Group A streptococcus, Pharyngitis, Respiratory infection, emm type
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