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Results of Korean antimicrobial resistance monitoring system (KARMS) in general hospitals, 2008-2015
- Date2017-11-09 20:42
- Update2017-11-09 20:42
- DivisionDivision of Strategic Planning for Emerging Infectious Diseases
- Tel043-719-7271
Results of Korean antimicrobial resistance monitoring system (KARMS) in general hospitals, 2008-2015
Kim Seung Hyun, Lee Kwang-Jun, Park Chan*
Division of Antimicrobial Resistance, Center for Infectious Disease, KNIH, KCDC
Hyukmin Lee
Department of Laboratory Medicine, Yonsei University College of Medicine
Background: Antimicrobial resistance (AMR) became a significant public health issue in recent decades. A multidisciplinary approach is required to overcome AMR, including appropriate operation of antimicrobial resistance surveillance systems. The Korean Antimicrobial Resistance Monitoring System (KARMS) has figured out the AMR situation of the most of tertiary-care hospitals in Korea during the past decade with the support of the Korean Centers for Disease Control and Prevention.
Current status: During the surveillance of KARMS, the trends of AMR rates showed fluctuations. The rate of methicillin-resistant Staphylococcus aureus (MRSA) infection continuously increased and reached a peak in 2009, but decreased from 2010, while the rate of infection with vancomycin-resistant enterococci (VRE) remained steadily high. Most gram negative strains showed an increase in AMR rates. The rate of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli infection continuously increased, and the one of ESBL-producing Klebsiella pneumoniae reached a peak in 2010 and has been sustained. The rate of fluoroquinolone resistance in E. coli was also increased. The rate of carbapenem resistance in Acinetobacter baumannii significantly increased from 2008 to 2015, but the one of imipenem resistance in Pseudomonas aeruginosa has not changed. Although the rates of carbapenem resistance in E. coli and K. pneumoniae remained low, the rates of susceptible strains continuously decreased.
Future Perspective: The KARMS is expected to not only contribute to monitoring the magnitude and trend of antimicrobial resistance in Korea but also play a key role in the GLobal Antimicrobial Resistance Surveillance System.
Keywords: Antimicrobial resistance, Fluoroquinolone, Carbapenem, Pseudomonas aeruginosa, Klebsiella pneumoniae
Kim Seung Hyun, Lee Kwang-Jun, Park Chan*
Division of Antimicrobial Resistance, Center for Infectious Disease, KNIH, KCDC
Hyukmin Lee
Department of Laboratory Medicine, Yonsei University College of Medicine
Background: Antimicrobial resistance (AMR) became a significant public health issue in recent decades. A multidisciplinary approach is required to overcome AMR, including appropriate operation of antimicrobial resistance surveillance systems. The Korean Antimicrobial Resistance Monitoring System (KARMS) has figured out the AMR situation of the most of tertiary-care hospitals in Korea during the past decade with the support of the Korean Centers for Disease Control and Prevention.
Current status: During the surveillance of KARMS, the trends of AMR rates showed fluctuations. The rate of methicillin-resistant Staphylococcus aureus (MRSA) infection continuously increased and reached a peak in 2009, but decreased from 2010, while the rate of infection with vancomycin-resistant enterococci (VRE) remained steadily high. Most gram negative strains showed an increase in AMR rates. The rate of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli infection continuously increased, and the one of ESBL-producing Klebsiella pneumoniae reached a peak in 2010 and has been sustained. The rate of fluoroquinolone resistance in E. coli was also increased. The rate of carbapenem resistance in Acinetobacter baumannii significantly increased from 2008 to 2015, but the one of imipenem resistance in Pseudomonas aeruginosa has not changed. Although the rates of carbapenem resistance in E. coli and K. pneumoniae remained low, the rates of susceptible strains continuously decreased.
Future Perspective: The KARMS is expected to not only contribute to monitoring the magnitude and trend of antimicrobial resistance in Korea but also play a key role in the GLobal Antimicrobial Resistance Surveillance System.
Keywords: Antimicrobial resistance, Fluoroquinolone, Carbapenem, Pseudomonas aeruginosa, Klebsiella pneumoniae
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